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Journal of Chromatography B: Biomedical Sciences and Applications
Copyright © 2001 Elsevier Science B.V. All rights reserved

Volume 725, Issue 1,
Pages 1-137 (2 April 1999)

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1.
Short Communication, Page 1

Journal Format-PDF (22 K)


2.
Combinatorial chemistry, automation and molecular diversity: new trends in the pharmaceutical industry, Pages 3-15
Luc Van Hijfte, Gilbert Marciniak and Nicolas Froloff
SummaryPlus | Article | Journal Format-PDF (173 K)

3.
Physico-chemical and biological analysis of true combinatorial libraries, Pages 17-37
J. A. Boutin, P. H. Lambert, S. Bertin, J. P. Volland and J. L. Fauchère
Abstract | Journal Format-PDF (207 K)

4.
Analyses of compound libraries obtained by high-throughput parallel synthesis: strategy of quality control by high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance techniques, Pages 39-47
Bertrand D. Duléry, Joëlle Verne-Mismer, Evelyne Wolf, C. Kugel and Luc Van Hijfte
SummaryPlus | Article | Journal Format-PDF (323 K)

5.
Impact of mass spectrometry on combinatorial chemistry, Pages 49-65
R. D. Süßmuth and G. Jung
SummaryPlus | Article | Journal Format-PDF (412 K)

6.
High-performance liquid chromatographic¯electrospray ionization mass spectrometric analyses for the integration of natural products with modern high-throughput screening, Pages 67-78
Mark A. Strege
SummaryPlus | Article | Journal Format-PDF (229 K)

7.
Nuclear magnetic resonance chromatography: applications of pulse field gradient diffusion NMR to mixture analysis and ligand¯receptor interactions, Pages 79-90
John S. Gounarides, Aidi Chen and Michael J. Shapiro
SummaryPlus | Article | Journal Format-PDF (279 K)

8.
Role of Fourier transform infrared spectroscopy in the rehearsal phase of combinatorial chemistry: a thin-layer chromatography equivalent for on-support monitoring of solid-phase organic synthesis, Pages 91-102
Bing Yan and Hans-Ulrich Gremlich
SummaryPlus | Article | Journal Format-PDF (364 K)

9.
Application of evaporative light scattering detection to the characterization of combinatorial and parallel synthesis libraries for pharmaceutical drug discovery, Pages 103-112
Bih H. Hsu, Edward Orton, Sheng-Yuh Tang and Robert A. Carlton
SummaryPlus | Article | Journal Format-PDF (229 K)

10.
Methods of screening combinatorial libraries using immobilized or restrained receptors, Pages 113-137
Charles P. WoodburyJr. and Duane L. Venton
SummaryPlus | Article | Journal Format-PDF (153 K)


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